study of antiradical activity, phospholipase A and 15-lipoxygenase inhibitory activity of eight malian medicinal plants used by traditional healers to treat inflammatory diseases

نویسندگان

چکیده

Pro-inflammatory enzymes play a key role in inflammatory processes and are potential targets of anti-inflammatory drugs. In this study, the objective was to evaluate antiradical activity extracts their ability inhibit phospholipase A 15-lipoxygenase activity. The hydroethanolic extract revealed strongest reducing power with an IC 7.29 ± 0.61 µg/mL. three most active on PLA were (IC 21.43 0.66 ?g/mL), 23.72 0.71 µg/mL), 24.49 0.39 µg/mL). best inhibitory 15-lipoxigenase obtained aqueous 18.35 1.26; 18.47 1.12 µg/mL respectively. present study showed that leaves roots have antioxidant effectively sPLA, 15-LOX pro-inflammatory

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ژورنال

عنوان ژورنال: Indian journal of pharmacy and pharmacology

سال: 2022

ISSN: ['2393-9079', '2393-9087']

DOI: https://doi.org/10.18231/j.ijpp.2022.031